| 12/03/2019 | |||||
| 12/03/2019 | Manchester City | 7:0 | FC Schalke 04 | ||
| Juventus | 3:0 | Atlético Madrid | |||
| 13/03/2019 | |||||
| 13/03/2019 | FC Barcelona | 5:1 | Olympique Lyon | ||
| Bayern München | 1:3 | Liverpool FC | |||
| 14/03/2019 | |||||
| 14/03/2019 | Inter | 0:1 | Eintracht Frankfurt | ||
| SL Benfica | 3:0 | Dinamo Zagreb | |||
| Slavia Praha | 4:3 | Sevilla FC | |||
| Arsenal FC | 3:0 | Stade Rennes | |||
| Villarreal CF | 2:1 | Zenit St. Petersburg | |||
| Dinamo Kiev | 0:5 | Chelsea FC | |||
| RB Salzburg | 3:1 | SSC Napoli | |||
| FK Krasnodar | 1:1 | Valencia CF | |||