| 20/10/2018 | |||||
| 20/10/2018 | Chelsea FC | 2:2 | Manchester United | ||
| AFC Bournemouth | 0:0 | Southampton FC | |||
| Cardiff City | 4:2 | Fulham FC | |||
| Manchester City | 5:0 | Burnley FC | |||
| Newcastle United | 0:1 | Brighton & Hove Albion | |||
| West Ham United | 0:1 | Tottenham Hotspur | |||
| Wolverhampton Wanderers | 0:2 | Watford FC | |||
| Huddersfield Town | 0:1 | Liverpool FC | |||
| 21/10/2018 | |||||
| 21/10/2018 | Everton FC | 16:00 | Crystal Palace | ||
| 22/10/2018 | |||||
| 22/10/2018 | Arsenal FC | 20:00 | Leicester City | ||
| # | Team | Pts | Pld | W | D | L | F | A | +/- | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Manchester City | 23 | 9 | 7 | 2 | 0 | 26 | 3 | 23 | |
| 2 | Liverpool FC | 23 | 9 | 7 | 2 | 0 | 16 | 3 | 13 | |
| 3 | Chelsea FC | 21 | 9 | 6 | 3 | 0 | 20 | 7 | 13 | |
| 4 | Tottenham Hotspur | 21 | 9 | 7 | 0 | 2 | 16 | 7 | 9 | |
| 5 | Arsenal FC | 18 | 8 | 6 | 0 | 2 | 19 | 10 | 9 | |
| 6 | AFC Bournemouth | 17 | 9 | 5 | 2 | 2 | 16 | 12 | 4 | |
| 7 | Watford FC | 16 | 9 | 5 | 1 | 3 | 13 | 12 | 1 | |
| 8 | Wolverhampton Wanderers | 15 | 9 | 4 | 3 | 2 | 9 | 8 | 1 | |
| 9 | Manchester United | 14 | 9 | 4 | 2 | 3 | 15 | 16 | -1 | |
| 10 | Leicester City | 12 | 8 | 4 | 0 | 4 | 14 | 12 | 2 | |
| 11 | Everton FC | 12 | 8 | 3 | 3 | 2 | 13 | 12 | 1 | |
| 12 | Brighton & Hove Albion | 11 | 9 | 3 | 2 | 4 | 10 | 13 | -3 | |
| 13 | Burnley FC | 8 | 9 | 2 | 2 | 5 | 10 | 17 | -7 | |
| 14 | Crystal Palace | 7 | 8 | 2 | 1 | 5 | 5 | 9 | -4 | |
| 15 | West Ham United | 7 | 9 | 2 | 1 | 6 | 8 | 14 | -6 | |
| 16 | Southampton FC | 6 | 9 | 1 | 3 | 5 | 6 | 14 | -8 | |
| 17 | Cardiff City | 5 | 9 | 1 | 2 | 6 | 8 | 19 | -11 | |
| 18 | Fulham FC | 5 | 9 | 1 | 2 | 6 | 11 | 25 | -14 | |
| 19 | Huddersfield Town | 3 | 9 | 0 | 3 | 6 | 4 | 18 | -14 | |
| 20 | Newcastle United | 2 | 9 | 0 | 2 | 7 | 6 | 14 | -8 |
| # | Name | Team | Goals | ||
|---|---|---|---|---|---|
| 1. | Eden Hazard | Chelsea FC | 7 | ||
| 2. | Kun Agüero | Manchester City | 6 | ||
| 3. | Harry Kane | Tottenham Hotspur | 5 | ||
| - | Aleksandar Mitrović | Fulham FC | 5 | ||
| - | Glenn Murray | Brighton & Hove Albion | 5 | ||
| 6. | Marko Arnautović | West Ham United | 4 | ||
| - | Pierre-Emerick Aubameyang | Arsenal FC | 4 | ||
| - | Joshua King | AFC Bournemouth | 4 | ||
| - | Alexandre Lacazette | Arsenal FC | 4 | ||
| - | Romelu Lukaku | Manchester United | 4 | ||
| - | Sadio Mané | Liverpool FC | 4 | ||
| - | Roberto Pereyra | Watford FC | 4 | ||
| - | Richarlison | Everton FC | 4 | ||
| - | Mohamed Salah | Liverpool FC | 4 | ||
| - | André Schürrle | Fulham FC | 4 | ||
| - | Gylfi Sigurðsson | Everton FC | 4 | ||
| - | Raheem Sterling | Manchester City | 4 | ||
| 18. | Bernardo Silva | Manchester City | 3 | ||
| - | Ryan Fraser | AFC Bournemouth | 3 | ||
| - | Andre Gray | Watford FC | 3 |
| # | Name | Team | Assists | ||
|---|---|---|---|---|---|
| 1. | Benjamin Mendy | Manchester City | 5 | ||
| 2. | Abdoulaye Doucouré | Watford FC | 4 | ||
| - | Olivier Giroud | Chelsea FC | 4 | ||
| - | Jóhann Guðmundsson | Burnley FC | 4 | ||
| - | José Holebas | Watford FC | 4 | ||
| - | Luciano Vietto | Fulham FC | 4 | ||
| - | Callum Wilson | AFC Bournemouth | 4 | ||
| 8. | Ryan Fraser | AFC Bournemouth | 3 | ||
| - | Eden Hazard | Chelsea FC | 3 | ||
| - | Kelechi Iheanacho | Leicester City | 3 | ||
| - | Raúl Jiménez | Wolverhampton Wanderers | 3 | ||
| - | Anthony Knockaert | Brighton & Hove Albion | 3 | ||
| - | Aaron Ramsey | Arsenal FC | 3 | ||
| 14. | Kun Agüero | Manchester City | 2 | ||
| - | David Silva | Manchester City | 2 | ||
| - | Matt Doherty | Wolverhampton Wanderers | 2 | ||
| - | Christian Eriksen | Tottenham Hotspur | 2 | ||
| - | Fernandinho | Manchester City | 2 | ||
| - | İlkay Gündoğan | Manchester City | 2 | ||
| - | Héctor Bellerín | Arsenal FC | 2 |